In maps: Five days of strikes across the Middle East
ReutersIsrael said it attacked "security headquarters" in the Iranian capital Tehran overnight, hitting the headquarters of the Basij paramilitary and missile sites across the city, as the US-Israeli war with Iran entered a fifth day.
Meanwhile, Israeli strikes in Lebanon have continued. Residents of southern Beirut were again warned to evacuate by the IDF, which said it was targeting the Iranian-backed militant group Hezbollah.
Further across the Middle East, Iranian strikes have hit the US consulate in Dubai and US air base at Al Udaid in Qatar - the biggest American facility in the region.
President Donald Trump has warned that the strikes could continue for four or five weeks, adding that the US has "capability to go far longer than that".
The US-based Human Rights Activists News Agency (HRANA) says 1,097 civilians have been reported killed in Iran since 28 February. Six American military personnel have been killed since the conflict began, according to the US Central Command.
Where have Israel and the US attacked?
The Israeli military announced extensive joint strikes with the US over the weekend, destroying air defences in western and central Iran.
Israel's military said its strikes on Tehran had targeted gatherings of senior political and security figures.
Iran's Supreme Leader, Ayatollah Ali Khamenei, who had led Iran since 1989, was killed during the first wave of strikes.
On Wednesday Israel's strikes targeted dozens of sites across the city, including the headquarters of the Basij paramilitary and missile launch pads and other defence systems, an Israel Defense Forces (IDF) spokesperson said.
BBC Verify has so far confirmed visual evidence of strikes on 13 different locations in Tehran, with 12 other towns and cities across Iran also hit.
At least 153 people were killed at a girls' school in Minab in the south of the country when it was hit by three missiles on Saturday, Iranian state media reported. The BBC has not been able to independently verify this.
Military sites were targeted in Kermanshah and Tabriz, and Iranian naval facilities in Konarak and Bandar Abbas in the south of the country.
Analysis of satellite imagery has revealed damage to at least three Iranian missile sites, and the nuclear facility at Natanz.
Damage to storage bunkers and other infrastructure is evident Konarak, Tabriz and Isfahan South, while at least three buildings have been damaged at the entrance to Natanz's underground enrichment complex.
US forces said they have sunk 17 Iranian naval ships and severely their naval headquarters.
Israel has expanded operations into Lebanon, where it is targeting Hezbollah, the militant group that has long been backed by Iran.
A hotel was among the buildings in the city hit by the attacks in Beirut on Wednesday. The night before Israeli officials said troops had entered Lebanon and were seizing "strategic areas" in order to prevent attacks on Israeli border communities.
The move came after Israel announced it was carrying out strikes in both Iran and Lebanon after Hezbollah launched missiles on Haifa earlier in the week.
Israel's air assault targeted Hezbollah's stronghold in the southern suburbs of Beirut and areas close to the city's airport, as well as sites in southern Lebanon. Blasts in the city continued into Tuesday morning.
Where has Iran attacked?
Iran has retaliated with strikes on Israel and US bases in the region, and has been blamed for air attacks on Gulf states.
On Tuesday night Saudi officials said the US Embassy in Riyadh had by hit by a pair of drones, causing some minor damage and sparking a small fire.
New Iranian strikes were reported on a major gas plant in Qatar, where the Ministry of Defense later said it had shot down two Iranian aircraft, seven missiles and five drones.
In the United Arab Emirates (UAE), which includes the tourist destinations of Dubai and Abu Dhabi, three people have been killed and several left injured, the country's defence ministry said on Sunday.
Kuwait's health ministry reported one death on Sunday. The Ali Al-Salem airbase was targeted by a number of ballistic missiles which were successfully intercepted, officials say.
The country's military downed three US fighter jets on Monday in "an apparent friendly fire incident", the US Central Command said. All six crew ejected safely and have been recovered, it says.
In neighbouring Iraq, three drones were reportedly downed on Monday over Irbil airport which hosts US-led coalition troops.
Bahrain's National Communication Centre said on Saturday that the service centre of the US Navy's Fifth Fleet had been "subjected to a missile attack".
Also in Bahrain, one verified clip, filmed from a moving vehicle, shows the moment a missile strikes. An explosion follows, sending fragments and debris into the air.
On Sunday evening a drone strike on the US naval base caused a major fire, one official told the BBC, but there were no reports of casualties.
Four people have been wounded by Iranian attacks in Bahrain, the official added.
In Saudi Arabia, a fire at the Ras Tanura refinery - run by the country's state oil company, Aramco - had been brought under control on Monday after two drones were intercepted, officials said.
Officials in Jordan, which borders Israel, said its armed forces had shot down ballistic missiles targeting its territory.
Oman's state news agency reported on Sunday that Duqm commercial port had been targeted by two drones, injuring one worker.
What happened in Cyprus?
An Iranian drone crashed into RAF Akrotiri at midnight (22:00 GMT Sunday), Cypriot President Nikos Christodoulides announced.
No casualties were reported and the base sustained "minimal damage", but the UK's Ministry of Defence said family members would be moved.
On Monday, a Cypriot government spokesperson said a further two drones heading towards RAF Akrotiri had been intercepted.
